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  3. 共用题干 More About Alzheimer's DiseaseScientists have developed skin tests tha...

共用题干 More About Alzheimer's DiseaseScientists have developed skin tests tha...

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问题 共用题干
More About Alzheimer's Disease
Scientists have developed skin tests that may be used in the future to identify people with Alzheimer's disease and may ultimately allow physicians to predict_______(51)is at risk of getting this neurological disorder.
The only current means of_____(52)the disease in a living patient is a long and expensive series of tests that eliminate every other cause of dementia（痴呆）.
"Since Alois Alzheimer described the_____(53)nearly a century ago,people have been trying to find a way to_____(54)diagnose it in its early stages,"said Patricia Grady,acting director of the National Institute of Neurological Disorders and Stroke in Bethesda,Maryland."This discovery,if_____(55),could prove a big step forward in our efforts to deal with and understand the disease."
Alzheimer ' 5 is the single greatest _________ ( 56 ) of mental deterioration（退化）in older people, affecting between 2.5 million and 4 million people in the United States_____(57).The devastating disorder gradually destroys memory and the ability to function,and eventually causes death.There is currently no known______（58)for the disease.
Researches______(59)that the skin cells of Alzheimer's patients have defects that interfere with their ability to regulate the flow of potassium（钾）in and out of the cells.The fact that the cell defects are present in the skin suggests that Alzheimer's______(60)from physiological changes throughout the body,and that dementia may be the first noticeable effect of these changes as the defects______(61)the cells in the brain,scientists said.
The flow of potassium is especially______(62)in cells responsible for memory formation.The scientists also found two other defects that affect the cells'supply, of calcium（钙）,another critical element.
One test developed by researches calls______(63)growing skin cells in a laboratory culture and then testing them with an electrical detector to determine if the microscopic tunnels that_______(64)the flow of potassium are open.Open potassium channels create a unique electrical signature.
A spokesman for the Alzheimer's Association said that if the validity of the diagnostic test can be proven it would be an important______(65),but cautioned that other promising tests for Alzheimer's have been disappointing.
选项 _________53
A:answer
B:effect
C:disease
D:study
答案C
解析此空处的词作宾语从句的主语，又根据句意可知，此处的主语应表示人，故选D。
文章中第一段中的皮肤反应测验的目的是为了诊断老年痴呆症。此处承接上文内容，故选D。
由后半句中的diagnose it可知，此处应填disease。
此空处的副词用来修饰之后的diagnose这个动词，比较四个选项，只有B项accurately （准确地）符合文意。
此处if引导的成分在句中作插入语，表达的意思为“如果确认的话”，故选C。
此处表达的意思为老年痴呆症是导致老年人脑力下降的唯一最大的原因。故此空处应填cause。
此处所表达的意思是：仅在美国，每年就有250万到400万美国人遭受老年痴呆症的困扰，alone表示“仅仅”，故选D。
本句话的意思为：目前还没有针对这种疾病的确切疗法。故此处用treatment。
本句中that之后陈述的是研究人员发现的一个事实，并没有表示预测、期望或警告。因此本题选A。
由文中可知，老年痴呆症是身体的生理病变引起的结果，result from意为“因……而产生”。
此处的含义为这种缺陷会对大脑中的细胞产生影响，故选A。
由本段第二句中的another critical element可知，此处应选critical。
call for为固定搭配，意为“要求，需要”。
此处表述的内容为控制钾的流动的管道。故此空应填govern。
根据句意可知，此项诊断性测试如果能得到验证，那将会是一个很重大的进步，故选C。
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